Oral cavity & oropharynx
Squamous cell carcinoma: variants
Papillary squamous cell carcinoma

Topic Completed: 1 November 2013

Minor changes: 22 May 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Papillary squamous cell carcinoma[TIAB] oral

Nat Pernick, M.D.
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Cite this page: Pernick N. Papillary squamous cell carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitypapillarycarcinoma.html. Accessed May 28th, 2020.
Definition / general
  • Rare; precursor lesion unknown
Microscopic (histologic) description
  • Malignant exophytic squamous proliferation with fibrovascular growth pattern of papilloma but marked cytologic atypia, irregular cords of invasion into stroma at base
  • Cells may resemble dysplastic basal and parabasal type cells or dysplastic squamous epithelium; variable keratosis
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