Oral cavity
Other benign tumors / conditions

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 April 2018, last major update November 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Plasmacytosis oral

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Cite this page: Pernick, N. Plasmacytosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavityplasmacytosis.html. Accessed January 24th, 2019.
Definition / general
  • No effective treatment
Gross description
  • Cobblestone or warty appearing mucosa, often at multiple sites
Microscopic (histologic) description
  • Dense subepithelial plasmacytosis with overlying psoriasiform epithelial hyperplasia
  • Plasma cells are mature but diffusely infiltrative
  • Polyclonal immunoglobulins
Differential diagnosis
  • Plasmacytoma: morphologically similar but monoclonal immunoglobulins