Oral cavity
Minor salivary gland tumors / lesions
Sialadenoma papilliferum

Topic Completed: 1 November 2013

Revised: 4 February 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Sialadenoma papilliferum minor salivary glands

Nat Pernick, M.D.
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Cite this page: Pernick N Sialadenoma papilliferum. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitysialadenoma.html. Accessed June 25th, 2019.
Definition / general
Gross description
  • Well circumscribed, round / oval, papillary tumor of mucosal surface
Microscopic (histologic) description
  • Biphasic, with well differentiated papillary hyperplastic squamous epithelium covering ductal component of cleft-like cystic spaces lined by cuboidal or columnar epithelium with occasional goblet cells
  • Variable oncocytes and squamous metaplasia; resembles Warthin tumor of parotid gland, papillary syringocystadenoma
Microscopic (histologic) images

Images hosted on other servers:

Papillary squamous
surface epithelium,
underlying ductal
structures and stains

Positive stains
Negative stains
Electron microscopy description
  • Oncocytic cell is predominant cell
  • Contains numerous mitochondria, parallel filaments within cell cytoplasm attached by desmosomes (Arch Pathol Lab Med 1986;110:523)
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