Oral cavity
Minor salivary gland tumors / lesions
Sialadenoma papilliferum

Author: Nat Pernick, M.D. (see Authors page)

Revised: 27 April 2018, last major update November 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Sialadenoma papilliferum minor salivary glands

Cite this page: Pernick, N. Sialadenoma papilliferum. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitysialadenoma.html. Accessed July 19th, 2018.
Definition / general
Gross description
  • Well circumscribed, round / oval, papillary tumor of mucosal surface
Microscopic (histologic) description
  • Biphasic, with well differentiated papillary hyperplastic squamous epithelium covering ductal component of cleft-like cystic spaces lined by cuboidal or columnar epithelium with occasional goblet cells
  • Variable oncocytes and squamous metaplasia; resembles Warthin tumor of parotid gland, papillary syringocystadenoma
Microscopic (histologic) images

Images hosted on other servers:

Papillary squamous
surface epithelium,
underlying ductal
structures and stains

Positive stains
Negative stains
Electron microscopy description
  • Oncocytic cell is predominant cell
  • Contains numerous mitochondria, parallel filaments within cell cytoplasm attached by desmosomes (Arch Pathol Lab Med 1986;110:523)