Oral cavity
Inflammatory (noninfectious) lesions
Tongue ulceration with eosinophilia

Author: Charu Thakral, M.D. (see Authors page)

Revised: 17 April 2018, last major update March 2013

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PubMed Search: Tongue ulceration with eosinophilia

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Cite this page: Thakral, C. Tongue ulceration with eosinophilia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitytongueeosinophilia.html. Accessed January 19th, 2019.
Definition / general
  • Resembles carcinoma clinically
  • Presumed due to crush injury of tongue muscle
  • Also called ulcerative eosinophilic granuloma, Riga-Fede disease, traumatic granuloma
Case reports
Clinical images

Images hosted on other servers:

70 year old woman:

Painful ulcer of tongue

Ill fitting prosthesis

Healing after removal of prosthesis

6 month old boy:

Ulcerative swelling

Microscopic (histologic) description
  • Eosinophils and other inflammatory cells in submucosa, mucosa, salivary glands
  • Dilated vessels often present
Microscopic (histologic) images

Images hosted on other servers:

Mixed cellular infiltrate