Ovary - nontumor
Massive edema of ovary
Reviewer: Shahid Islam, M.D., (see Reviewers page)
Revised: 5 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.
● Tumor-like enlargement of ovary due to edema fluid
● First described in 1969 (Obstet Gynecol 1969;34:564)
● Patients present with pain, abdominal mass, menstrual irregularities, virilization, precocious puberty, Meig’s syndrome (with ascites and pleural effusion, eMedicine)
● May be due to partial torsion of mesovarium leading to interference of venous / lymphatic drainage
● Usually young women
● Right-sided involvement is more common
● Marked ovarian enlargement, watery cut surface, no necrosis
● Marked edema of stroma surrounding follicles and clusters of luteinized cells
● Stroma around vessels and in superficial cortical zone is normal
● Variable stromal luteinization
Clusters of lutein cells lie in the edematous stroma
Loose stroma with occasional inflammatory cells #1; #2
● Fibroma: circumscribed, tumor cells replace ovarian architecture
● Krukenberg tumor: usually bilateral, signet ring cells present
● Am J Surg Pathol 1979;3:11,
Arch Pathol Lab Med 1979;103:42
End of Ovary - nontumor > Non-neoplastic cysts/other > Massive edema of ovary
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