Ovary - nontumor
Non-neoplastic cysts / other

Author: Aurelia Busca, M.D. (see Authors page)
Editor: Carlos Parra-Herran, M.D.

Revised: 3 October 2016, last major update October 2016

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Cholelithiasis [title] ovary

Cite this page: Cholelithiasis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarynontumorcholelithiasis.html. Accessed October 27th, 2016.
Definition / General
  • The presence of gallstones in the peritoneal cavity, attached to the ovary, usually as a result of intraperitoneal spillage of gallbladder contents during laparoscopic cholecystectomy
  • Gallstones or bile are spilled in the peritoneal cavity during laparoscopic cholecystectomy and can cause local hemorrhage, inflammation / infection and adhesions
  • Complications of intraperitoneal spillage of gallbladder contents include localized infection, septicemia, intestinal obstruction and pelvic migration
  • A review of 1059 laparoscopic cholecystectomy cases reported intraoperative perforation of the gallbladder in 306 (29%) of cases, out of which 103 cases had spillage of both bile and gallstones; intraperitoneal spillage of gallbladder contents was associated with an increased risk of intra-abdominal abscess (2.9% vs 0 in cases of intact gallbladder removal) (J Gastrointest Surg 1997;1:85)
Clinical Features
  • The patients may be asymptomatic or present with chronic pain or infectious symptoms
Case Reports
  • Depends on the stone location and clinical presentation
  • Can include local drainage and evacuation of the stones if there is an abscess formation or surgical resection if there is concern for neoplasia
Gross Images

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Gallstone adherent to ovary

Micro Description
  • The gallstones cause mesothelial proliferation, hemorrhage and result in adhesion formation
Differential Diagnosis