Ovary - nontumor
Nonneoplastic cysts / other

Topic Completed: 1 October 2016

Revised: 5 February 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Cholelithiasis [title] ovary

Aurelia Busca, M.D., Ph.D.
Carlos Parra-Herran, M.D.
Page views in 2018: 425
Page views in 2019 to date: 337
Cite this page: Busca A Cholelithiasis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarynontumorcholelithiasis.html. Accessed September 18th, 2019.
Definition / general
  • The presence of gallstones in the peritoneal cavity, attached to the ovary, usually as a result of intraperitoneal spillage of gallbladder contents during laparoscopic cholecystectomy
  • Gallstones or bile are spilled in the peritoneal cavity during laparoscopic cholecystectomy and can cause local hemorrhage, inflammation / infection and adhesions
  • Complications of intraperitoneal spillage of gallbladder contents include localized infection, septicemia, intestinal obstruction and pelvic migration
  • A review of 1059 laparoscopic cholecystectomy cases reported intraoperative perforation of the gallbladder in 306 (29%) of cases, out of which 103 cases had spillage of both bile and gallstones; intraperitoneal spillage of gallbladder contents was associated with an increased risk of intra-abdominal abscess (2.9% vs 0 in cases of intact gallbladder removal) (J Gastrointest Surg 1997;1:85)
Clinical features
  • The patients may be asymptomatic or present with chronic pain or infectious symptoms
Case reports
  • Depends on the stone location and clinical presentation
  • Can include local drainage and evacuation of the stones if there is an abscess formation or surgical resection if there is concern for neoplasia
Gross images

Images hosted on other servers:

Gallstone adherent to ovary

Microscopic (histologic) description
  • The gallstones cause mesothelial proliferation, hemorrhage and result in adhesion formation
Differential diagnosis
Back to top