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Ovary-nontumor

Non-neoplastic cysts / other

Endosalpingiosis

Reviewer: Mohiedean Ghofrani, M.D. (see Reviewers page)
Revised: 25 August 2011, last major update August 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Presence of benign glands, lined by tubal-type epithelium

Epidemiology
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● Typically in women of reproductive age

Sites
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● Most commonly pelvic peritoneum covering uterus, fallopian tubes, ovaries and cul-de-sac
● Other sites also reported

Etiology
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● Origin from secondary mullerian system (pelvic and lower abdominal mesothelium) is favored
● Association with chronic salpingitis suggests implantation of sloughed tubal epithelium as another possibility
● Also, association with ovarian serous tumors, usually borderline, suggests maturation of tumor implants

Clinical features
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● Almost always an incidental finding

Case reports
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● Cystic mass involving ovary and full thickness of uterine fundus (Ultrasound Obstet Gynecol 2008;32:106)
● With psammoma bodies (J Reprod Med 1991;36:675)

Gross description
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● Usually grossly inapparent, but may present as multiple white to yellow microcysts (1-2 mm)
● Rarely seen as larger cysts

Micro description
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● Benign glands and tubules lined by tubal type cells
● May be surrounded by loose stroma with chronic inflammatory infiltrate
● Calcifications or psammoma bodies are common (Mod Pathol 2003;16:219)
● Smooth contours
● Variable papillae beneath the peritoneal surface

Micro images
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Glands lined by ciliated epithelium lie in fibrous stroma (AFIP)


Ciliated, secretory and intercalated cells line the cystic space (AFIP)


Lymph node


Omentum: CD34 and calretinin

Differential Diagnosis
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● Noninvasive or invasive ovarian implants
● Mesonephric remnants: have smooth muscle under epithelial lining

End of Ovary-nontumor > Non-neoplastic cysts / other > Endosalpingiosis

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