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Ovary-nontumor

Non-neoplastic cysts / other

Heterotopic ovarian splenoma


Reviewer: Mohiedean Ghofrani, M.D., Southwest Washington Medical Center (see Reviewers page)
Revised: 9 August 2011, last major update August 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Form of heterotopic splenic hamartoma consisting of red pulp tissue without associated white pulp, in otherwise normal ovary

Epidemiology
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● Very rare

Case reports
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● 45 year old woman with heavy menses (Arch Pathol Lab Med 2001;125:1483)

Micro description
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● Interanastomosing vascular channels of splenic, sinusoidal red pulp
● Sinuses are lined by cuboidal to flattened cells with ovoid and grooved, bland-looking nuclei

Micro images
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Heterotopic ovarian splenoma

Positive stains
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● von Willebrand factor, CD8 (splenic lining cells)

EM description
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● Weibel-Palade bodies, lysosomes

EM images
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Weibel-Palade body

End of Ovary-nontumor > Non-neoplastic cysts / other > Heterotopic ovarian splenoma


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