Ovary - nontumor
Nonneoplastic cysts / other
Ovarian pregnancy

Author: Shahid Islam, M.D. (see Authors page)

Revised: 19 September 2017, last major update June 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Ovarian pregnancy [title] "loattrfree full text"[sb]

Cite this page: Islam, S. Ovarian pregnancy. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovaryovarianpregnancy.html. Accessed June 19th, 2018.
Definition / general
  • 1 - 3% of ectopic pregnancies; often conceptus dies or involutes spontaneously
  • Resembles tubal pregnancy due to similar symptoms (abdominal pain, amenorrhea, abnormal vaginal bleeding) and risk factors (pelvic inflammatory disease, prior pelvic surgery, IUD [Eur J Obstet Gynecol Reprod Biol 2004;114:92], use of progesterone only minipill)
  • Due to retention of ovum in ovarian operculum and continued entrapment within ruptured ovarian follicle; sperm fertilizes entrapped ovum and implantation occurs within ovary
  • Difficult to diagnose clinically or even intraoperatively
  • Patients have excellent prognosis for future fertility; recurrence is virtually nonexistent

Spiegelberg criteria:
  1. Intact ipsilateral tube, clearly separate from the ovary
  2. Gestational sac within or replacing the ovary
  3. Sac connected to the uterus by the ovarian ligament
  4. Histologically proven ovarian tissue located in the sac wall (Arch Gynaekol 1878;13:73)
Case reports
Clinical images

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Gross description
Gross images

Images hosted on PathOut server:

Ovary is replaced by
a hemorrhagic mass
containing a small,
pale yellow fetus (AFIP)

Images hosted on other servers:

Hemorrhagic cavity

Ovary containing gestational sac

Microscopic (histologic) description
  • Evidence of pregnancy (chorionic villi, trophoblastic tissue), ovarian tissue in wall of gestational sac
Microscopic (histologic) images

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Corpus luteum,
chorionic villi and

Chorionic villi surrounded by corpus luteum