Ovary tumor
Other tumors not specific to ovary
Adenoid cystic and basaloid carcinoma

Authors: Nalini Gupta, M.D. (see Authors page)

Revised: 17 June 2016, last major update December 2013

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed search: Adenoid cystic carcinoma ovary
Cite this page: Adenoid cystic and basaloid carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumoradenoidcystic.html. Accessed October 22nd, 2016.
Definition / General
  • First described in 1995 by Eichhorn and Scully (Mod Pathol 1995;8:731)
  • Very rare ovarian tumors
  • Postulated to be of surface epithelial origin
  • Adenoid cystic carcinomas are more aggressive than basaloid carcinomas, present at older age
  • Postulated origin is through metaplasia of coelomic / surface epithelium
  • Rarely may be teratomatous origin
Clinical Features
  • Abdominal pain, unilateral abdominal mass
  • Adenoid cystic carcinoma: mean age 67 years, range 60 to 78 years
  • Basaloid carcinoma: mean age 49 years, range 19 to 65 years
Case Reports
Gross Description
Micro Description
  • Small uniform and basaloid cells in tubular pattern with cribriform and focal solid areas
  • Multiple round hyaline stromal cylinders
  • Minimal pleomorphism or mitotic activity, no necrosis
  • With myoepithelial differentiation, tumor cells are ovoid to spindled (Arch Pathol Lab Med 2000;124:1529, Mod Pathol 1996;9:413)
Micro Images

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Adenoid cystic carcinoma

Basaloid and ameloblastoma-like features



Positive Stains
  • Cytokeratins CAM 5.2 and AE1/3, CEA
  • Peripheral cells positive for muscle-specific actin, S100, GFAP
Negative Stains
  • Alcain blue, alpha inhibin, ER, PR, desmin, AFP
Electron Microscopy Description
  • Myoepithelial component shows convoluted nuclei and filamentous structures associated with dense bodies
Differential Diagnosis