Adenoid cystic and basaloid carcinoma

Ovary tumor
Other tumors not specific to ovary
Adenoid cystic and basaloid carcinoma

Authors: Nalini Gupta, M.D. (see Authors page)

Revised: 17 June 2016, last major update December 2013

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed search: Adenoid cystic carcinoma ovary

Table of Contents

Definition / General

First described in 1995 by Eichhorn and Scully (Mod Pathol 1995;8:731)
Very rare ovarian tumors
Postulated to be of surface epithelial origin
Adenoid cystic carcinomas are more aggressive than basaloid carcinomas, present at older age

Pathophysiology

Postulated origin is through metaplasia of coelomic / surface epithelium
Rarely may be teratomatous origin

Clinical Features

Abdominal pain, unilateral abdominal mass
Adenoid cystic carcinoma: mean age 67 years, range 60 to 78 years
Basaloid carcinoma: mean age 49 years, range 19 to 65 years

Case Reports

23 year old woman (Arch Pathol Lab Med 2000;124:1529)
45 year old woman (Mod Pathol 1996;9:413)

Treatment

Unilateral salpingo-oophorectomy (Mod Pathol 1996;9:413) with or without adjuvant radiotherapy (Int J Radiat Oncol Biol Phys 2000;46:551)
Chemotherapy for metastatic disease

Gross Description

Unilateral
Encapsulated
Solid with small cystic spaces (Mod Pathol 1995;8:731)

Micro Description

Small uniform and basaloid cells in tubular pattern with cribriform and focal solid areas
Multiple round hyaline stromal cylinders
Minimal pleomorphism or mitotic activity, no necrosis
With myoepithelial differentiation, tumor cells are ovoid to spindled (Arch Pathol Lab Med 2000;124:1529, Mod Pathol 1996;9:413)

Micro Images

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