Ovary tumor
Other tumors not specific to ovary
Adenoid cystic and basaloid carcinoma

Topic Completed: 1 December 2013

Revised: 13 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed search: Adenoid cystic carcinoma ovary

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Cite this page: Gupta N Adenoid cystic and basaloid carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumoradenoidcystic.html. Accessed December 9th, 2019.
Definition / general
  • First described in 1995 by Eichhorn and Scully (Mod Pathol 1995;8:731)
  • Very rare ovarian tumors
  • Postulated to be of surface epithelial origin
  • Adenoid cystic carcinomas are more aggressive than basaloid carcinomas, present at older age
  • Postulated origin is through metaplasia of coelomic / surface epithelium
  • Rarely may be teratomatous origin
Clinical features
  • Abdominal pain, unilateral abdominal mass
  • Adenoid cystic carcinoma: mean age 67 years, range 60 to 78 years
  • Basaloid carcinoma: mean age 49 years, range 19 to 65 years
Case reports
Gross description
Microscopic (histologic) description
  • Small uniform and basaloid cells in tubular pattern with cribriform and focal solid areas
  • Multiple round hyaline stromal cylinders
  • Minimal pleomorphism or mitotic activity, no necrosis
  • With myoepithelial differentiation, tumor cells are ovoid to spindled (Arch Pathol Lab Med 2000;124:1529, Mod Pathol 1996;9:413)
Microscopic (histologic) images

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Adenoid cystic carcinoma

Basaloid and ameloblastoma-like features



Positive stains
  • Cytokeratins CAM 5.2 and AE1/3, CEA
  • Peripheral cells positive for muscle-specific actin, S100, GFAP
Negative stains
  • Alcain blue, alpha inhibin, ER, PR, desmin, AFP
Electron microscopy description
  • Myoepithelial component shows convoluted nuclei and filamentous structures associated with dense bodies
Differential diagnosis
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