Ovary tumor
Other tumors not specific to ovary
Benign papillary mesothelioma

Author: Nalini Gupta, M.D. (see Authors page)

Revised: 29 June 2016, last major update December 2014

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PubMed Search: Benign papillary mesothelioma ovary
Cite this page: Benign papillary mesothelioma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumorb9papmeso.html. Accessed October 26th, 2016.
Definition / General
  • Unusual variant of epithelial mesothelioma (JDMS 2013;6:1)
  • Occurs mainly in the peritoneum
  • Tumors of < 2 cm are considered benign while larger tumors are more likely to disseminate (J Gynecol Surg. 2013;29:59)
  • Peritoneum, pericardium, and tunica vaginalis
Clinical Features
  • Adominal mass, pain
  • Ultrasonography shows an ovarian mass
Case Reports
  • Salpingo-oophorectomy
  • Yellowish firm, multinodular ovarian mass
Gross Description
  • Yellowish firm, multinodular ovarian mass
Micro Description
  • Thin fibrovascular papillae lined by relatively uniform cuboidal mesothelial cells
  • Psammoma bodies are occasionally encountered
Micro Images

Images hosted on other servers:

Well-differentiated papillary mesothelium

Strongly positive for calretinin

Positive Stains
Negative Stains
Differential Diagnosis
  • Diffuse malignant mesothelioma (DMM): cytological atypia, abnormal mitoses and bizarre cells
  • Reactive mesothelial hyperplasia
  • Serous papillary adenocarcinoma: CEA positive