Ovary tumor
Mucinous tumors
Mucinous borderline tumors, intestinal type

Authors: Shahrzad Ehdaivand, M.D. (see Authors page)

Revised: 14 September 2018, last major update July 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Ovarian mucinous borderline intestinal

Related topics: General, Endocervical
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Cite this page: Ehdaivand, S. Mucinous borderline tumors, intestinal type. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumorborderlinemucinousintestinal.html. Accessed October 19th, 2019.
Definition / general
  • 85% of borderline mucinous cases
  • Older patients, not associated with endometriosis
  • Excellent prognosis
  • Intestinal type are further divided:
    • With atypia only
    • With intraepithelial carcinoma
    • With microinvasion
Gross images

Images hosted on PathOut server:

Mucinous cystic tumor

Images hosted on other servers:

Seromucinous borderline tumor

Microscopic (histologic) description
  • With atypia only:
    • Resemble dysplastic intestinal epithelium with goblet cells, neuroendocrine cells and occasional Paneth cells
    • Neoplastic cells have hyperchromasia, crowding, increased mitosis, and stratification forming papillae with thin fibrous cores
    • Lumens contain mucin

  • With intraepithelial carcinoma:
    • Resemble high grade dysplasia of intestines with severe cytologic atypia without stroma invasion
    • Papillae without stroma and cribriforming is often present

  • With microinvasion:
    • Invasive foci measuring less than 10 mm2 and < 3 mm in greatest dimension
    • Foci of stromal invasion with desmoplastic response or small clusters of cells, occasionally cribriform with eosinophilic cytoplasm with minimal/absent stromal reaction (Hum Pathol 1996;27:521)
    • Desmoplastic stroma has pale nuclear staining, fibrous reaction or edema in stroma
    • Areas of mucin extravasation with inflammatory response are not diagnostic of invasion; this includes a brisk inflammatory reaction with histocytes and large areas of necrosis
Microscopic (histologic) images

Images hosted on PathOut server:

Mucinous cystic tumor

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