Ovary tumor
Other tumors not specific to ovary
Endometrial stromal sarcoma

Author: Nalini Gupta, M.D. (see Authors page)

Revised: 10 October 2018, last major update June 2016

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Endometrial stromal sarcoma [title] ovary
Cite this page: Gupta, N. Endometrial stromal sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumoress.html. Accessed November 21st, 2018.
Definition / general
  • Composed of cells resembling endometrial stromal cells in the proliferative stage
  • Rare in extra-uterine sites
  • Most common site is uterus
  • Extrauterine sites rare - includes ovary, fallopian tube, pelvic cavity, abdominal cavity, and retroperitoneum (Int J Gynecol Pathol 1993;12:282)
Clinical features
Radiology description
  • Ultrasound / USG: solid cystic mass
  • CT scan with IV contrast: peripheral enhancement
Prognostic factors
Case reports
  • Salphingo-opherectomy
Gross description
Microscopic (histologic) description
  • High or low grade
  • Low grade: infiltrative and diffuse proliferation of uniform round or oval cells, abundant small vessels
  • Undifferentiated: pleomorphic round / oval to spindled cells, high mitotic rate, necrosis
Microscopic (histologic) images

Images hosted on PathOut server:

High grade tumor

Monotonous cells

Endometrium-like glands


Images hosted on other servers:

Various images

With sex cord-like differentiation

Reticulin stain

Metastatic to omentum

Positive stains
Negative stains
Differential diagnosis