Other tumors
Endometrial stromal sarcoma

Topic Completed: 1 June 2016

Minor changes: 11 March 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: Endometrial stromal sarcoma [title] ovary

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Cite this page: Gupta N. Endometrial stromal sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumoress.html. Accessed September 23rd, 2020.
Definition / general
  • Composed of cells resembling endometrial stromal cells in the proliferative stage
  • Rare in extra-uterine sites
  • Most common site is uterus
  • Extrauterine sites rare - includes ovary, fallopian tube, pelvic cavity, abdominal cavity, and retroperitoneum (Int J Gynecol Pathol 1993;12:282)
Clinical features
Radiology description
  • Ultrasound / USG: solid cystic mass
  • CT scan with IV contrast: peripheral enhancement
Prognostic factors
Case reports
  • Salphingo-opherectomy
Gross description
Microscopic (histologic) description
  • High or low grade
  • Low grade: infiltrative and diffuse proliferation of uniform round or oval cells, abundant small vessels
  • Undifferentiated: pleomorphic round / oval to spindled cells, high mitotic rate, necrosis
Microscopic (histologic) images

AFIP images

Various images

With sex cord-like differentiation

Reticulin stain

Metastatic to omentum

Images hosted on other servers:

High grade tumor

Monotonous cells

Endometrium-like glands


Positive stains
Negative stains
Differential diagnosis
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