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Ovary tumor
Sex cord stromal tumors
Granulosa cell tumor - juvenile

Reviewer: Shahrzad Ehdaivand, M.D. (see Reviewers page)
Revised: 23 October 2013, last major update December 2012
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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Case reports
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Treatment
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Gross description
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Gross images
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Contributed by Dr. Hanni Gulwani, New Delhi (India) - 3 year old girl with breast enlargement:

Mostly solid tumor with focal cystic change

Micro description
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Micro images
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Gross, H&E and inhibin

Case of Week #59



Contributed by Dr. Hanni Gulwani, New Delhi (India) - 3 year old girl with breast enlargement:

Primordial follicles in normal ovary

Poorly formed follicles with mucoid secretions

Well-demarcated tumor with pseudolobular pattern
and compressed normal ovary at periphery


Compact spindle cell areas with hemangiopericytoma like pattern

Loose edematous areas with abortive follicles


Spindle cells are SMA+

Vimentin+;

High MIB-1 expression

ER+ and PR+


Virtual slides
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39 cm tumor

Positive stains
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Negative stains
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Molecular description
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Differential diagnosis
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End of Ovary tumor > Sex cord stromal tumors > Granulosa cell tumor - juvenile


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