Ovary tumor
Brenner tumors
Malignant Brenner tumor


Topic Completed: 1 December 2012

Revised: 6 March 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: ovarian malignant Brenner tumor

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Cite this page: Ehdaivand S. Malignant Brenner tumor. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumormalignantbrenner.html. Accessed March 28th, 2020.
Definition / general
  • Atypical cytology and stromal invasion
  • May be bilateral
  • Better prognosis than urothelial (transitional cell) carcinoma
Gross images

AFIP images

Soft tan areas with small cysts, firm white areas

Solid nodules

Microscopic (histologic) description
  • Resembles urothelial, squamous or undifferentiated carcinoma, but associated with benign or borderline Brenner component; stromal invasion is present
Microscopic (histologic) images

AFIP images

Malignant transitional cells invade cyst wall

Two benign Brenner nests

Early squamous differentiation


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