Ovary tumor
Other tumors not specific to ovary

Topic Completed: 1 December 2014

Revised: 14 February 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Osteosarcoma [title] ovary

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Cite this page: Gupta N Osteosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumorosteosarcoma.html. Accessed February 18th, 2020.
Definition / general
  • Osteosarcomas (OS) involving ovary are of three types:
    1. Pure/primary
    2. Arising in teratoma
    3. Metastatic
  • Pure osteosarcomas do not have the mesenchymal component of a biphasic tumor; are very rare, aggressive tumors (Int J Gynecol Pathol 2007;26:21)
Clinical features
  • Rapidly enlarging lower abdominal mass
  • Vaginal bleeding
Radiology description
  • CT: Heterogenous mass with or without areas of calcification / ossification
  • MRI: Heterogenous mass with solid and cystic areas
Prognostic factors
Case reports
  • Surgery with adjuvant chemotherapy (cisplatin-doxorubicin)
Clinical images

Images hosted on other servers:
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Large recurrent solid pelvic mass

Gross description
  • Solid cystic tumor mass, mean size of 13 cm
Microscopic (histologic) description
  • Scattered areas of osteoid formation with anaplastic cells
  • Multinucleate giant cells, areas of cystic degeneration / necrosis
  • No epithelial component
Microscopic (histologic) images

Images hosted on other servers:
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Arising from teratoma

Positive stains
Negative stains
Differential diagnosis
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