Ovary tumor
Serous tumors

Topic Completed: 1 May 2012

Minor changes: 7 February 2019

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PubMed Search: Ovarian serous tumors

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Cite this page: Ehdaivand S Serous tumors - general. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumorserous.html. Accessed June 1st, 2020.
Definition / general
  • 25% of all ovarian tumors
  • 60% benign, 15% borderline, 30% malignant
  • May also occur as primary tumors of peritoneal surface
  • If cystic, name as serous "cystadeno..."
  • If prominent fibrous component, name as adenofibroma or adenocarcinofibroma
Microscopic (histologic) description
  • Tall, columnar, ciliated epithelial cells, resembling fallopian tube, filled with clear serous fluid
  • Carcinomas frequently have psammoma bodies (concentric calcifications)
  • Squamous metaplasia unlikely (in contrast to endometrioid tumors)
Positive stains
Negative stains
  • CEA and CDX2
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