Pancreas
Pancreatitis
Herpes simplex pancreatitis

Author: Deepali Jain, M.D. (see Authors page)

Revised: 8 December 2017, last major update August 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Herpes simplex[TIAB] pancreatitis[TIAB]

Cite this page: Jain, D. Herpes simplex pancreatitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/pancreasHSV.html. Accessed October 20th, 2018.
Definition / general
Gross description
  • Small, discrete foci of hemorrhagic necrosis
Microscopic (histologic) description
  • Parenchymal necrosis, hemorrhage, minimal fat necrosis, mild neutrophilic infiltrate compared to intensity of necrosis (Arch Pathol Lab Med 2003;127:231)
  • Atrophic acinar cells
  • Numerous eosinophilic intranuclear inclusions with clear halos (Cowdry type A), many multinucleated giant cells with hyperchromatic irregular nuclei and eosinophilic cytoplasm
  • Some nuclei have basophilic, ground glass / smudged appearance
Microscopic (histologic) images

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Various images