Pancreas
Neuroendocrine neoplasms
ACTH secreting tumors

Author: Deepali Jain, M.D. (see Authors page)

Revised: 22 December 2017, last major update August 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: ACTH secreting tumors pancreas

Cite this page: Jain, D. ACTH secreting tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/pancreasacth.html. Accessed May 26th, 2018.
Definition / general
  • Not a WHO diagnosis
  • Rare pancreatic endocrine neoplasm producing adrenocorticotrophic hormone (ACTH)
  • Causes Cushing syndrome: central obesity, muscle weakness, glucose intolerance, hypertension
Case reports
Gross images

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Spleen, adrenal gland and pancreas with tumor

Microscopic (histologic) images

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AFIP images:

ACTH producing tumor with Cushing syndrome



Images hosted on other servers:

Rounded nests of densely packed cells

66 year old man with ultrasound guided biopsy: H&E and ACTH antibody