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Pancreas

Tumors

Schwannoma


Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 24 November 2012, last major update August 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● May arise from extrapancreatic nerve plexus (Surgery 2012 Oct 24)
● Rare, mean age 60 years, M=F, 2/3 partially cystic, typical histology (Mod Pathol 1998;11:1178)
● 62 year old man with microcystic/reticular variant (Pathol Int 2011;61:88)

Gross images
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Cut surface composed of solid, myxomatous and hemorrhagic areas


Cystic tumor of pancreatic tail

Micro images
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Left/middle: spindle cell proliferation with interlacing and palisading patterns; right: myxoid / edematous degeneration with hemorrhage, hemosiderin and hyalinized and dilated vascular walls (Antoni B)


Giant malignant schwannoma of pancreatic body and tail, which involved transverse colon

Cytology images
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Cystic fluid: a-scattered spindle cells with background hemosiderin-laden histiocytes; b-tumor cells have fine granular chromatin with single prominent nucleolus; c-some tissue fragments are composed of spindle cells; d-S100+

End of Pancreas > Tumors > Schwannoma


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