Pancreas
Cysts
True cysts

Author: Deepali Jain, M.D. (see Authors page)

Revised: 11 December 2017, last major update August 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: True cyst[TIAB] pancreas

Cite this page: Jain, D. True cysts. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/pancreastrue.html. Accessed December 13th, 2017.
Congenital / dysgenetic cysts
Definition / general

Case reports

Microscopic (histologic) images

Images hosted on PathOut server:

Congenital cyst: cysts are lined by small nonmucin producing cuboidal cells and are embedded in fibrous stroma

Cysts of cystic fibrosis
Definition / general
Dermoid cysts
Definition / general
  • Seen in young patients (2nd - 3rd decade)


Case reports

Gross images

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Tail of pancreas cyst



Microscopic (histologic) images

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Tail of pancreas cyst

Epidermoid cysts
Definition / general
  • May be present within an intrapancreatic spleen (Pancreas 2011;40:956)
  • In tail, unilocular, typically contain concentric enzymatic concretions, may communicate with acinar system
  • Squamoid cyst of pancreatic ducts; has thin wall lined by transitional / squamous cells without keratinization or granular layer


Case reports
  • 62 year old man with intrapancreatic spleen containing epidermoid cyst (JOP 2011;12:279)


Microscopic (histologic) images

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62 year old man: intrapancreatic spleen has multiple cysts with stratified squamous epithelium that is CEA+

Foregut cysts attached to pancreas
Definition / general
  • Rare; unilocular, smooth surface with clear mucoid material, ciliated epithelium resembles bronchogenic cyst but no respiratory glands, no cartilage and two smooth muscle layers (Am J Surg Pathol 1996;20:476)


Case reports

Gross images

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Foregut cyst (0.9 cm) attached to pancreas; retroperitoneal margins are inked



Microscopic (histologic) images

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Foregut cyst attached to pancreas

Foregut cyst and immunostains of lining - a: cyst compresses bile duct (arrow);
b: cyst is lined by thin epithelial layer (arrowhead) covering loose connective
tissue without smooth muscle bundles or cartilage; * depicts normal pancreas;
c: pseudostratified ciliated epithelium with interspersed goblet cells (arrows)



Cytology images

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Ciliated foregut cyst - FNA

Mesothelial cysts
Definition / general
  • May be multiple and involve pancreas, liver, kidney or other abdominal structures


Case reports
Pancreatic hamartoma
Case reports

Microscopic (histologic) images

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Various images

Nonepithelial cysts
Definition / general
  • Includes endometrial cyst, lymphangioma, pseudocysts, parasitic cyst
Pancreatic tissue derived cysts
Definition / general
  • May appear in thorax or mediastinum, as components of gastroenteric duplication cysts, intralobar pulmonary sequestrations, teratomas or rarely from ectopic pancreatic tissue (Mod Pathol 1996;9:210)
  • Paraduodenal wall cyst (cystic dystrophy): patients with paraduodenal (groove) pancreatitis, cysts may enlarge and adhere to duodenal wall, mimicking duodenal duplication; lined by granulation tissue, may be partly lined by ductal epithelium (Semin Diagn Pathol 2004;21:247)


Gross images

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Ectopic pancreas with cystic change in mediastinum



Microscopic (histologic) images

Images hosted on other servers:

Ectopic pancreas with cystic change in mediastinum