Pancreas
Neuroendocrine neoplasms
VIPoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 22 December 2017, last major update August 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: VIPoma[TI] pancreas

Cite this page: Jain, D. VIPoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/pancreasvipoma.html. Accessed August 20th, 2018.
Definition / general
Clinical features
  • Diarrhea (cholera-like), hypokalemia, achlorhydria
  • Neural crest tumors (ganglioneuroma, neuroblastoma, neurofibroma, pheochromocytoma) and G cell tumors produce similar symptoms
  • Also contains pancreatic polypeptide, calcitonin, alpha chain of hCG
  • May be locally invasive or metastastic
Case reports
Gross images

Images hosted on other servers:

Pancreatic head tumor

Microscopic (histologic) images

Images hosted on PathOut server:

AFIP images:

Endocrine carcinoma with glandular pattern

Pancreatic VIPoma



Images hosted on other servers:

Interconnecting nests and trabeculae of uniform cuboidal cells with granular cytoplasm and central round nuclei

Electron microscopy images

Images hosted on PathOut server:

AFIP images:

Pancreatic VIPoma