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Pancreas
WHO classification of Tumors
General

Author: Andrey Bychkov, M.D., Ph.D., Nat Pernick, M.D. (see Authors page)

Revised: 2 August 2017, last major update July 2017

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

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Table of Contents
WHO (2010) | Additional references
Cite this page: WHO classification of tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/pancreaswho.html. Accessed August 21st, 2017.
WHO (2010)
  • Epithelial tumors
    • Benign
      • 8551/0 Acinar cell cystadenoma  
      • 8441/0 Serous cystadenoma, NOS
    • Premalignant lesions  
      • 8148/2 Pancreatic intraepithelial neoplasia, grade 3 (PanIN-3)  
      • 8453/0 Intraductal papillary mucinous neoplasm (IPMN) with low or intermediate grade dysplasia  
      • 8453/2 Intraductal papillary mucinous neoplasm (IPMN) with high grade dysplasia  
      • 8503/2 Intraductal tubulopapillary neoplasm (ITPN)  
      • 8470/0 Mucinous cystic neoplasm (MCN) with low or intermediate grade dysplasia  
      • 8470/2 Mucinous cystic neoplasm (MCN) with high grade dysplasia
    • Malignant lesions  
      • 8500/3 Ductal adenocarcinoma  
      • 8560/3 Adenosquamous carcinoma  
      • 8480/3 Mucinous adenocarcinoma  
      • 8576/3 Hepatoid carcinoma  
      • 8510/3 Medullary carcinoma, NOS  
      • 8490/3 Signet ring cell carcinoma  
      • 8020/3 Undifferentiated carcinoma  
      • 8035/3 Undifferentiated carcinoma with osteoclast-like cells  
      • 8550/3 Acinar cell carcinoma  
      • 8551/3 Acinar cell cystadenocarcinoma  
      • 8453/3 Intraductal papillary mucinous carcinoma (IPMN) with an associated invasive carcinoma  
      • 8552/3 Mixed acinar ductal carcinoma  
      • 8154/3 Mixed acinar neuroendocrine carcinoma  
      • 8154/3 Mixed acinar neuroendocrine ductal carcinoma  
      • 8154/3 Mixed ductal neuroendocrine carcinoma  
      • 8470/3 Mucinous cystic neoplasm (MCN) with an associated invasive carcinoma  
      • 8971/3 Pancreatoblastoma  
      • 8441/3 Serous cystadenocarcinoma, NOS  
      • 8452/3 Solid pseudopapillary neoplasm
    • Neoplasms of the neuroendocrine pancreas (updated to the 2017 classification - Lloyd: WHO Classification of Tumours of Endocrine Organs (IARC WHO Classification of Tumours), Fourth Edition, 2017)
      • Nonfunctioning (nonsyndromic) neuroendocrine tumors
      • 8151/3 Insulinoma
      • 8152/3 Glucagonoma
      • 8156/3 Somatostatinoma
      • 8153/3 Gastrinoma
      • 8155/3 VIPoma
      • Serotonin producing tumours with and without carcinoid syndrome
      • ACTH producing tumour with Cushing syndrome
      • 8246/3 Pancreatic neuroendocrine carcinoma (poorly differentiated neuroendocrine neoplasm)
      • Mixed neuroendocrine nonneuroendocrine neoplasms
        • Mixed ductal neuroendocrine carcinomas
        • Mixed acinar neuroendocrine carcinomas
  • Mesenchymal tumours
    • 9170/0 Lymphangioma, NOS  
    • 8850/0 Lipoma, NOS  
    • 8815/1 Solitary fibrous tumor  
    • 9260/3 Ewing sarcoma  
    • 8806/3 Desmoplastic small round cell tumor  
    • Perivascular epithelioid cell neoplasm
  • Lymphomas
    • 9680/3 Diffuse large B cell lymphoma (DLBCL), NOS
  • Secondary tumours
    • Secondary tumours of the pancreas
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