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Parathyroid gland


Atypical adenoma

Reviewer: Monika Roychowdhury, M.D. (see Reviewers page)
Revised: 17 February 2013, last major update January 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

Clinical features

● Has some features of malignancy (broad fibrous bands crossing the tumor, trabecular growth, pseudocapsular invasion [clusters of parathyroid cells trapped within the capsule in 50%]), but no vascular invasion, no metastases, rarely increased mitotic activity (Hum Pathol 2003;34:54)
● Unpredictable clinical behavior

Case reports

● 63 year old woman with ectopic atypical parathyroid lipoadenoma (J Bone Miner Metab 2012 Dec 22 [Epub ahead of print])

Micro images

Atypical adenoma showing characteristic dense collagenous bands

Atypical adenoma extending close to margins of excision, often due to fibrosis and adherence to adjacent structures

End of Parathyroid gland > Neoplasms > Atypical adenoma

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