Table of ContentsDefinition / general | Diagnosis | Case reports | Treatment | Clinical images | Microscopic (histologic) images
Cite this page: Roychowdhury M. Calciphylaxis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/parathyroidcalciphylaxis.html. Accessed May 27th, 2020.
Definition / general
- Rare and life threatening condition of vascular calcification, first described in 1962, that causes ischemic damage to skin (usually lower extremity) and other organs (G Ital Nefrol 2012;29:674, Hum Pathol 1995;26:1055)
- Also known as calcific uremic arteriopathy (CUA), calcifying panniculitis, vascular calcification-cutaneous necrosis syndrome
- Affects 1 - 4% of dialysis patients; associated with primary, secondary or tertiary hyperparathyroidism
- 60 - 80% mortality
- Bilateral, symmetrical, superficial skin lesions with persistence of dorsal pulses; confirm with biopsy