Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Parathyroid gland

General

Ectopic parathyroid tissue


Reviewer: Monika Roychowdhury, M.D. (see Reviewers page)
Revised: 16 February 2013, last major update January 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
=========================================================================

● Estimated incidence of 35%; due to aberrant migration during early stages of development
● Common etiology of persistent or recurrent hyperparathyroidism when missed at initial diagnosis (Exp Clin Endocrinol Diabetes 2012;120:604)
● Often symptomatic due to hyperplasia associated with secondary hyperparathyroidism
● Often symmetrical from side to side, even when ectopic, making localization somewhat easier (eMedicine)
● Can undergo adenomatous change, and cause primary hyperparathyroidism, hypercalcemia and acute pancreatitis (World J Surg Oncol 2004;2:41)
● Inability to identify may lead to failure of parathyroid surgery

Sites
=========================================================================

● Axilla (Int Surg 2004;89:6)
● Mediastinum (Ann Thorac Surg 1997;64:238)
● Pyriform sinus (Arch Otolaryngol Head Neck Surg 2002;128:71)
● Thyroid gland (Nihon Rinsho 1995;53:920)
● Vagus nerves of children (Arch Pathol Lab Med 1988;112:304)
● Ectopic inferior parathyroids are most frequently found in anterior mediastinum, in association with thymus or thyroid gland; ectopic superior parathyroids are usually at tracheoesophageal groove or retroesophageal region (Exp Clin Endocrinol Diabetes 2012;120:604)

Case reports
=========================================================================

● 86 year old woman with neck pain and difficulty swallowing (Case of the Week #108)

Micro images
=========================================================================



Case of the week #108


Thymic tissue contains a mass of parathyroid cells

Stain images (parathyroid glands are on upper left):

   
Cytokeratin cocktailChromogranin     SynaptophysinParathyroid hormone

End of Parathyroid gland > General > Ectopic parathyroid tissue


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).