Parathyroid gland - Pseudohypoparathyroidism

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Parathyroid gland

Pseudohypoparathyroidism

Reviewer: Monika Roychowdhury, M.D. (see Reviewers page)
Revised: 29 January 2013, last major update January 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Resistance of organs to PTH (Wikipedia-pseudohypoparathyroidism)

Type 1:
● Deficiency of Gs alpha protein or abnormalities in the level of the hormone receptor complex
● Associated with decreased cAMP response
● Also called Albright hereditary osteodystrophy (round facies, short stature, short metacarpal and metatarsal bones)

Type 2:
● Blunted response to second messenger

End of Parathyroid gland > Pseudohypoparathyroidism

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