Parathyroid gland
General
Parathyroid cysts

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 27 July 2018, last major update January 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Parathyroid cysts[TI]

Cite this page: Roychowdhury, M. Parathyroid cysts. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/parathyroidpthcysts.html. Accessed August 16th, 2018.
Definition / general
  • Patients usually are normocalcemic and present with an asymptomatic mass
  • May be hyperplastic gland (Am J Clin Pathol 1982;77:104), adenoma with cystic degeneration, heterotopic salivary gland-like tissue (Am J Surg Pathol 2000;24:837)
  • Can diagnose by FNA if PTH in fluid (Am J Clin Pathol 1986;86:776)
  • Cystic parathyroid lesions often contain turbid or colored fluid
  • Functional parathyroid cysts more common than nonfunctional parathyroid cysts (Arch Surg 2009;144:52)
  • During resection, cyst rupture should be avoided and patients with large cysts should be managed expectantly to forestall the development of symptomatic hypocalcemia
Radiology images

Images hosted on PathOut server:

Contributed by Ayana Suzuki, Cytotechnologist, Japan:

Large multilocular cyst

Case reports
Treatment
Clinical images

Images hosted on PathOut server:

Contributed by Ayana Suzuki, Cytotechnologist, Japan:

Clear fluid

Gross description
  • Usually large, in inferior glands
  • Unilocular, thin walled with clear fluid containing PTH
Microscopic (histologic) description
  • Lined by flattened parathyroid epithelium without nodules
  • May contain granular material resembling colloid
Microscopic (histologic) images

Images hosted on other servers:

Fibroadipose tissue
containing islands of
parathyroid tissue

Positive stains
Negative stains