Parathyroid gland
Hyperparathyroidism
Secondary chief cell hyperplasia

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 11 April 2018, last major update January 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Secondary chief cell hyperplasia

Cite this page: Roychowdhury, M. Secondary chief cell hyperplasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/parathyroidsecondary.html. Accessed July 16th, 2018.
Definition / general
  • Gland may be normal sized with microscopic hypercellularity or be grossly enlarged
  • Hyperplasia due to reduced mean serum calcium level
  • "Secondary" is based on historical, chemical and laboratory findings (not due to primary alteration in PTH)
Microscopic (histologic) images

Images hosted on other servers:

Enlarged glands due to chronic renal failure with impaired phosphate excretion

Differential diagnosis
  • Adenoma: rim of normal, nonhyperplastic tissue around the mass and at least one normal parathyroid gland