Penis and scrotum
Neoplastic lesions of scrotum
Aggressive angiomyxoma


Topic Completed: 1 May 2010

Revised: 14 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Aggressive angiomyxoma scrotum

Alcides Chaux, M.D.
Antonio L. Cubilla, M.D.
Page views in 2018: 513
Page views in 2019 to date: 528
Cite this page: Chaux A, Cubilla AL. Aggressive angiomyxoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/penscrotumaggressiveangio.html. Accessed September 23rd, 2019.
Definition / general
Epidemiology
Clinical features
Case reports
Clinical images

Images hosted on other servers:

Marked swelling

Scrotal mass

Gross description
  • Irregular and infiltrative borders
  • Gelatinous, mucoid cut surface
  • Tumor size 3 - 60 cm (usually > 5 cm)
Gross images

Images hosted on other servers:

Gelatinous cut surface

Ill defined mass

Microscopic (histologic) description
  • Hypocellular, stellate / spindle stromal cells with delicate cytoplasmic processes
  • Prominent myxoid (mucicarmine positive) to collagenous stroma
  • Abundant small to medium sized blood vessels, many with hypertrophy / hyalinization (Am J Surg Pathol 1992;16:1059)
  • Extravasation of erythrocytes is common
  • No atypia or significant mitotic activity
Microscopic (histologic) images

AFIP images

Delicate vessels and myxoid stroma



Images hosted on other servers:

Thick walled vessels, myxoid to collagenous stroma

CD34+

Trichrome+

Prominent myxoid stroma



Spermatic cord:

Spindle cells

Variable sized vessels

Perivascular spindled cells

Vimentin+

CD34+

Scattered PR+



Vulvar tumor

Negative stains
Molecular / cytogenetics description
Differential diagnosis
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