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Penis and scrotum

Other malignancies

Clear cell sarcoma

 

Editors: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Author/Reviewers page)

Revised: 12 May 29 April 2010, last major update May 2010

Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.

 

Definition

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● Malignant tumor composed of clear neoplastic cells similar to those observed in malignant melanoma of soft parts

● See also clear cell sarcoma in Soft Tissue chapter part 3

 

Terminology

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● Also called malignant melanoma of soft parts

● ICD-O coding is 9044/3

 

Epidemiology

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● Very rare

 

Case reports

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● 10 year old boy with tumor at root of penis (Hum Pathol 1986;17:423)

 

Micro images

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   FIGURE 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author             FIGURE 2 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Soft tissue tumors                                             MiTF+

 

Positive stains

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● S100, other melanocytic markers

 

Cytogenetic / molecular description

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● Derived from t(12;22)(q13;q12)

 

Electron microscopy description

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● Melanosomes

 

End of Penis and scrotum > Other malignancies > Clear cell sarcoma

 

 

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