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Penis and scrotum
Other malignancies
Kaposiís sarcoma

Reviewer: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Reviewers page)
Revised: 19 June 2013, last major update May 2010
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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Epidemiology
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Sites
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Etiology
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Clinical features
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Case reports
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Treatment
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Clinical images
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42 year old homosexual with
ulcerated plaque in coronal sulcus

36 year old HIV+ man with extensive
involvement of glans causing meatal stricture


Tumor forms discrete nodules

Nodules/papules in glans

Gross description
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Micro description
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Micro images
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Low power

High power; note the slit-like blood vessels


Other sites:

Patch stage; with promontory sign (right)

Plaque stage


Nodular stage

Resembles cavernous hemangioma

H&E and D2-40


CD31+

CD34+


Lymphangioma-like variant


Lymphangiectactic variant

Bullous variant


Telangiectatic variant; CD31+ (right)


Hyperkeratotic (verrucous) variant

Hyperkeratotic and
lymphangioma-like features


Keloidal variant

Micronodular variant


Pyogenic granuloma-like variant

Ecchymotic variant


Regressed lesion


Positive stains
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Negative stains
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Differential diagnosis
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End of Penis and scrotum > Other malignancies > Kaposiís sarcoma


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