Penis and scrotum - Liposarcoma

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Penis and scrotum

Neoplastic lesions of scrotum

Liposarcoma

Editors: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Author/Reviewers page)

Revised: 22 May 2010, last major update May 2010

Definition

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● Most scrotal liposarcomas are spermatic cord neoplasms presenting as an intrascrotal mass

● ICD-0: 8850/3

● See also Testis chapter

Terminology

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● Dual lineality / combined lipoleiomyosarcoma: foci of liposarcoma and leiomyosarcoma (Am J Surg Pathol 1993;17:905)

Clinical features

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● Paratesticular well differentiated liposarcomas have good prognosis with no metastases, although >50% recur, sometimes late (Am J Surg Pathol 2003;27:40)

Gross images

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Lobulated yellow mass

Micro description (Histopathology)

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● Similar to liposarcoma elsewhere

● Subtypes include well-differentiated (including inflammatory-Hinyokika Kiyo 2006;52:961), myxoid / round cell (J Med Assoc Thai 2005;88:1302) and pleomorphic (Am J Surg Pathol 2010 Apr 28 [Epub ahead of print])

● May have meningothelial-like whorls (Yonsei Med J 2003;44:392)

Micro images

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Entrapped lipoblasts (arrow), multinucleated

giant cells (arrowhead) and sclerosis

Paratesticular liposarcoma

End of Penis and scrotum > Neoplastic lesions of scrotum > Liposarcoma

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