Penis and scrotum
Other malignancies
Primary lymphoma


Topic Completed: 1 April 2010

Revised: 14 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Primary lymphoma penis

Alcides Chaux, M.D.
Antonio L. Cubilla, M.D.
Page views in 2018: 83
Page views in 2019 to date: 91
Cite this page: Chaux A, Cubilla AL. Primary lymphoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/penscrotumlymphoma.html. Accessed July 18th, 2019.
Definition / general
  • Primary penile lymphomas are exceedingly rare
  • Secondary involvement is somewhat common in disseminated disease
Sites
  • All penile compartments may be affected
Clinical features
  • Non-Hodgkin B or T cell lymphoma is more common than Hodgkin lymphoma
  • Confirmation and phenotyping is done by immunohistochemistry
Case reports
Treatment
Clinical images

AFIP images

5 cm ulcer of dorsum of penis

Postchemotherapy

Gross description
  • Fleshy white neoplasm, nonspecific ulceration
Gross images

AFIP images

Irregular, shaggy, white-gray mass

Microscopic (histologic) description
  • Dense infiltrate of atypical lymphocytes
Microscopic (histologic) images

AFIP images

Large cell lymphoma

Differential diagnosis
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