Penis and scrotum
Other malignancies
Primary lymphoma

Authors: Antonio Cubilla, M.D., Alcides Chaux, M.D. (see Authors page)

Revised: 6 April 2018, last major update April 2010

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Primary lymphoma penis

Page views in 2018: 83
Page views in 2019 to date: 10
Cite this page: Cubilla, A., Chaux, A. Primary lymphoma. website. Accessed January 22nd, 2019.
Definition / general
  • Primary penile lymphomas are exceedingly rare
  • Secondary involvement is somewhat common in disseminated disease
  • All penile compartments may be affected
Clinical features
  • Non-Hodgkin B or T cell lymphoma is more common than Hodgkin lymphoma
  • Confirmation and phenotyping is done by immunohistochemistry
Case reports
Clinical images

Images hosted on PathOut server:

5 cm ulcer of dorsum of penis


Gross description
  • Fleshy white neoplasm, nonspecific ulceration
Gross images

Images hosted on PathOut server:

Irregular, shaggy, white-gray mass

Microscopic (histologic) description
  • Dense infiltrate of atypical lymphocytes
Microscopic (histologic) images

Images hosted on PathOut server:

Large cell lymphoma

Differential diagnosis