Penis and scrotum
Inflammatory lesions
Mondor phlebitis

Authors: Antonio Cubilla, M.D., Alcides Chaux, M.D. (see Authors page)

Revised: 30 March 2018, last major update February 2010

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Mondor phlebitis

Cite this page: Cubilla, A., Chaux, A. Mondor phlebitis. website. Accessed December 15th, 2018.
Definition / general
  • Also called superficial thrombophlebitis, Mondor disease or (incorrectly) nonvenereal sclerosing lymphangitis
  • Preferentially affects the superficial dorsal penile vein
  • Firm, subcutaneous cord-like structure(s) along dorsal shaft of penis or around coronal sulcus, due to massive thrombosis of superficial venous plexus of penis
  • Causes: neoplasm, mechanical trauma during vigorous intercourse following sexual abstinence, sickle cell disease (J Am Osteopath Assoc 2003;103:102), long airline flight (Int J STD AIDS 2005;16:510), varicose vein surgery (J R Soc Med 2001;94:292) or herpes simplex infection
Clinical features
  • Firm, subcutaneous cord-like structures, mostly parallel to coronal sulcus
  • Foreskin and dorsal midline of penile shaft can also be affected
  • Pain and tenderness in a minority of cases, especially during erection
  • Almost always self limited (spontaneous regression in 4 - 8 weeks) but associated with considerable psychological stress
  • Temporary sexual abstinence
Clinical images

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Deep venous thrombosis

Firm, cord-like lesion

Gross description
  • Firm, subcutaneous cord-like structures along dorsal shaft of penis or around coronal sulcus
Microscopic (histologic) description
  • Prominent vessels with plump endothelial cells and thickened (sclerotic) blood vessel walls (mainly veins), with occasional vessel showing complete occlusion of lumen
  • Perivascular inflammatory infiltrate composed of lymphocytes, histiocytes and plasma cells
  • No evidence of lymphatic involvement
Microscopic (histologic) images

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Arteriole and venule with plump endothelial cells

Differential diagnosis
  • Cutaneous polyarteritis nodosa: vasculitis involving small and medium sized arteries of the dermis and subcutaneous tissue