Penis and scrotum
Inflammatory lesions
Mondor phlebitis


Topic Completed: 1 February 2010

Revised: 13 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Mondor phlebitis

Alcides Chaux, M.D.
Antonio L. Cubilla, M.D.
Page views in 2018: 414
Page views in 2019 to date: 738
Cite this page: Chaux A, Cubilla AL. Mondor phlebitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/penscrotummondors.html. Accessed November 13th, 2019.
Definition / general
Terminology
  • Also called superficial thrombophlebitis, Mondor disease or (incorrectly) nonvenereal sclerosing lymphangitis
Epidemiology
Sites
  • Preferentially affects the superficial dorsal penile vein
Etiology
  • Firm, subcutaneous cord-like structure(s) along dorsal shaft of penis or around coronal sulcus, due to massive thrombosis of superficial venous plexus of penis
  • Causes: neoplasm, mechanical trauma during vigorous intercourse following sexual abstinence, sickle cell disease (J Am Osteopath Assoc 2003;103:102), long airline flight (Int J STD AIDS 2005;16:510), varicose vein surgery (J R Soc Med 2001;94:292) or herpes simplex infection
Clinical features
  • Firm, subcutaneous cord-like structures, mostly parallel to coronal sulcus
  • Foreskin and dorsal midline of penile shaft can also be affected
  • Pain and tenderness in a minority of cases, especially during erection
  • Almost always self limited (spontaneous regression in 4 - 8 weeks) but associated with considerable psychological stress
Treatment
  • Temporary sexual abstinence
Clinical images

Images hosted on other servers:

Deep venous thrombosis

Firm, cord-like lesion

Gross description
  • Firm, subcutaneous cord-like structures along dorsal shaft of penis or around coronal sulcus
Microscopic (histologic) description
  • Prominent vessels with plump endothelial cells and thickened (sclerotic) blood vessel walls (mainly veins), with occasional vessel showing complete occlusion of lumen
  • Perivascular inflammatory infiltrate composed of lymphocytes, histiocytes and plasma cells
  • No evidence of lymphatic involvement
Microscopic (histologic) images

Images hosted on other servers:

Arteriole and venule with plump endothelial cells

Differential diagnosis
  • Cutaneous polyarteritis nodosa: vasculitis involving small and medium sized arteries of the dermis and subcutaneous tissue
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