Penis and scrotum
Staging of penile carcinoma

Topic Completed: 1 January 2018

Revised: 14 February 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Staging of penile carcinoma[TI]

Debra Zynger, M.D.
Page views in 2018: 1,249
Page views in 2019 to date: 951
Cite this page: Zynger D. Staging of penile carcinoma. website. Accessed August 24th, 2019.

Pathologic TNM staging of penile squamous cell carcinoma, AJCC 8th edition
Primary tumor (pT)
  • pTX: Cannot be assessed
  • pT0: No evidence of primary tumor
  • pTa: Noninvasive carcinoma (broad pushing penetration is permitted)
  • pTis: Carcinoma in situ
  • pT1a: Subepithelial invasion without lymphovascular invasion, perineural invasion or grade 3
  • pT1b: Subepithelial invasion with lymphovascular invasion, perineural invasion or grade 3
  • pT2: Invasion of corpus spongiosum
  • pT3: Invasion of corpus cavernosum
  • pT4: Invasion of adjacent structures including scrotum, prostate and pubic bone
Regional lymph nodes (pN)
  • pNX: Cannot be assessed
  • pN0: No regional lymph node metastasis
  • pN1: Metastasis in 1 or 2 unilateral inguinal node(s)
  • pN2: Metastasis in 3 or more unilateral inguinal nodes OR bilateral inguinal nodes
  • pN3: Extranodal extension OR metastasis to pelvic lymph node
    (superficial / deep inguinal, pelvic [external iliac, internal iliac / hypogastric, obturator, pelvic NOS])
Distant metastasis (pM)
  • pM1: Distant metastasis (ex: common iliac, aortic / caval lymph node)
AJCC prognostic stage groups
Stage group 0is: Tis N0 M0
Stage group 0a: Ta N0 M0
Stage group I: T1a N0 M0
Stage group IIA: T1b - 2 N0 M0
Stage group IIB: T3 N0 M0
Stage group IIIA: T1 - 3 N1 M0
Stage group IIIB: T1 - 3 N2 M0
Stage group IV: T4 N1 - 3, X M0
T1 - 4, X N3 M0
T1 - 4, X   N1 - 3, X   M1
Gross images

Contributed by Debra Zynger, M.D.



Microscopic (histologic) images

Contributed by Debra Zynger, M.D.

CIS / PeIN (pTis)

Subepithelial invasion (pT1a)

Invasion of corpora spongiosum (pT2)

Inguinal lymph node metastasis (pN1)

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