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Penis and scrotum
Squamous cell carcinoma and variants
Verrucous carcinoma

Reviewer: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Reviewers page)
Revised: 28 June 2013, last major update May 2010
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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Terminology
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Epidemiology
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Sites
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Etiology
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Clinical features
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Treatment
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Clinical images
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Tumor of glans penis

Gross description
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Gross images
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A large, destructive, cauliflower-like
mass has extensively replaced the penis

Papillary lesion involving the glans

Micro description
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Micro images
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Pushing border

Well-differentiated keratinized tumor cells


Minimal atypia

Pronounced exophytic tumor


Sharp interface between
neoplasm and lamina propria

Tumor cells have bland cytologic features


Various images


Contributed by Dr. Alcides Chaux and Dr. Antonio Cubilla:

Mixed (hybrid) usual-verrucous carcinoma

Exophytic growth

Acanthosis


Negative stains
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Differential diagnosis
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End of Penis and scrotum > Squamous cell carcinoma and variants > Verrucous carcinoma


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