Penis and scrotum
Neoplastic lesions of scrotum
Posttraumatic spindle cell nodule of scrotum

Topic Completed: 1 May 2010

Revised: 15 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Spindle cell nodule scrotum

Alcides Chaux, M.D.
Antonio L. Cubilla, M.D.
Page views in 2018: 134
Page views in 2019 to date: 148
Cite this page: Chaux A, Cubilla AL. Posttraumatic spindle cell nodule of scrotum. website. Accessed September 23rd, 2019.
Definition / general
  • More common in urinary bladder, rarely reported in scrotum
  • Also called postoperative spindle cell nodule
  • Wide age range
  • Trauma related tumor-like lesion
Clinical features
  • Circumscribed mass or diffuse progressive enlargement of scrotal wall
  • Arises weeks to months after surgery or trauma
  • No recurrence after local excision
Case reports
Microscopic (histologic) description
  • Monomorphic, dense, spindle cell proliferations forming irregular nodules in wall of hematoma
  • Dense collagenous matrix
  • Low mitotic rate and no cytological atypia
Microscopic (histologic) images

AFIP images

Interlacing fascicles of myofibroblasts

Uniform cells are mixed with inflammatory cells

Images hosted on other servers:


L: muscularis propria; R: spindle cell nodule

Positive stains
Molecular / cytogenetics description
Differential diagnosis
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