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Penis and scrotum
Infectious disorders
Syphilis

Reviewer: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Reviewers page)
Revised: 9 July 2013, last major update February 2010
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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Terminology
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Epidemiology
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Etiology
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Clinical features
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Laboratory
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Case reports
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Treatment
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Clinical images
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Primary chancre


Atrophic scar with condylomata lata

Sharply delineated lesion

Two well circumscribed, minimally elevated lesions
with sharp borders and necrotic centers are present


Secondary rash / lesions:

Palm, limbs and hands


Back


Face, teeth


"Kissing" lesions

Various images


Micro description
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Micro images
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Lymph nodes


Perivascular dermal infiltrate

Lesion characterized by acanthosis and a dense
perivascular lymphoplasmacytic infiltrate in dermis


Darkfield microscopy

Chorioretinitis of congenital syphilis


Patchy infiltrate

Epithelioid cells surrounded by lymphomononuclear cells


Various images


Virtual slides
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Syphilic chancre

Positive stains
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Electron microscopy images
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Spirochete in culture

Differential diagnosis
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End of Penis and scrotum > Infectious disorders > Syphilis


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