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Penis and scrotum
Squamous cell carcinoma and variants
Warty carcinoma

Reviewer: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Reviewers page)
Revised: 9 July 2013, last major update January 2010
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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Terminology
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Epidemiology
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Sites
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Clinical features
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Prognostic factors
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Treatment
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Gross description
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Gross images
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10-38: exophytic, cauliflower-like white
to tan tissue replaces the glans (fig A)

Exophytic neoplasm covering the entire
glans and extending to the foreskin

Micro description
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Micro images
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10-39: undulating, complex and hyperkeratotic
papillae with infiltration at the base

High power view of papillae with hyperkeratosis,
parakeratosis and koilocytotic atypia


Figure 1D


Contributed by Dr. Alcides Chaux and Dr. Antonio Cubilla:

Conspicuous koilocytosis, nuclear pleomorphism and atypical parakeratosis


Positive stains
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Molecular description
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Differential diagnosis
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End of Penis and scrotum > Squamous cell carcinoma and variants > Warty carcinoma


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