Placental gross / microscopic abnormalities, nonneoplastic
Acute chorionic vasculitis

Topic Completed: 1 September 2011

Revised: 15 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Acute chorionic vasculitis

Mandolin S. Ziadie, M.D.
Page views in 2018: 1,005
Page views in 2019 to date: 933
Cite this page: Ziadie MS. Acute chorionic vasculitis. website. Accessed November 21st, 2019.
Definition / general
  • Vasculitis involving fetal vessels of chorionic plate or umbilical cord
Microscopic (histologic) description and grading
  • Neutrophilic infiltration into the wall of umbilical cord / chorionic plate vessels or Wharton jelly
  • Severity is determined by the number of vessels involved and the presence of necrosis
  • Umbilical vasculitis: specify number of vessels with / without funisitis (extension into Wharton jelly)
  • Chorionic plate vasculitis: duration of inflammation may be estimated based on severity of associated maternal response: short (subchorionitis, chorionitis), intermediate (chorioamnionitis) or long (subnecrotizing, necrotizing chorioamnionitis)
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