Placenta
Infectious conditions
Acute villitis


Topic Completed: 1 September 2011

Revised: 15 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Placenta acute villitis

Mandolin S. Ziadie, M.D.
Page views in 2018: 1,553
Page views in 2019 to date: 942
Cite this page: Ziadie MS. Acute villitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentaacutevillitis.html. Accessed July 21st, 2019.
Definition / general
  • Usually due to ascending infection from vaginal tract, causes premature rupture of membranes
  • Associated with prematurity and sepsis in first days of life
  • Present in 5 - 25% of placentas
  • Associated with hemorrhagic vasculitis, vascular obliteration
  • Not due to meconium staining, which does not directly cause inflammation
Etiology
  • Usually associated with E. coli and group B strep
Grading
  • Mild ( < 5% of villi)
  • Moderate (5 - 25%)
  • Severe (25%+)
Microscopic (histologic) description
  • Neutrophils in the fetal capillaries and distal villi
  • Organisms are often visible
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