Placental findings in specific newborn/fetal or maternal conditions
Beckwith-Wiedemann syndrome

Reviewers: Mandolin Ziadie, M.D. (see Authors page)

Revised: 29 March 2016, last major update October 2011

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Beckwith-Wiedemann syndrome placental
Cite this page: Beckwith-Wiedemann syndrome. website. Accessed April 23rd, 2017.
Definition / General
  • Congenital disorder of overgrowth associated with congenital macroglossia, macrosomia, midline abdominal wall defects, hypoglycemia and an increased risk for pediatric tumors, including Wilms tumor and hepatoblastoma
  • See Adrenal gland and paraganglia chapter
  • Etiology
  • Related to genetic abnormalities of 11p15
  • Micro Description
  • Placental hydrops involving stem villi
  • No trophoblastic hyperplasia is present (Hum Pathol 1991;22:591)