Placenta - Beckwith-Wiedemann syndrome

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Placenta

Placental findings in specific newborn/fetal or maternal conditions

Beckwith-Wiedemann syndrome

Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 12 November 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Congenital disorder of overgrowth associated with congenital macroglossia, macrosomia, midline abdominal wall defects, hypoglycemia and an increased risk for pediatric tumors, including Wilms tumor and hepatoblastoma

Etiology
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● Related to genetic abnormalities of 11p15

Micro description
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● Placental hydrops involving stem villi
● No trophoblastic hyperplasia is present (Hum Pathol 1991;22:591)

End of Placenta > Placental findings in specific newborn/fetal or maternal conditions > Beckwith-Wiedemann syndrome

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