Placental findings in specific newborn/fetal or maternal conditions
Beckwith-Wiedemann syndrome

Reviewers: Mandolin Ziadie, M.D. (see Authors page)

Revised: 29 March 2016, last major update October 2011

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Beckwith-Wiedemann syndrome placental
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Cite this page: Beckwith-Wiedemann syndrome. website. Accessed August 21st, 2019.
Definition / general
  • Congenital disorder of overgrowth associated with congenital macroglossia, macrosomia, midline abdominal wall defects, hypoglycemia and an increased risk for pediatric tumors, including Wilms tumor and hepatoblastoma
  • See Adrenal gland and paraganglia chapter
  • Etiology
  • Related to genetic abnormalities of 11p15
  • Microscopic (histologic) description
  • Placental hydrops involving stem villi
  • No trophoblastic hyperplasia is present (Hum Pathol 1991;22:591)
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