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Placenta

Placental findings in specific newborn/fetal or maternal conditions

Blighted ovum

Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 12 November 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Failure of development or early embryonic demise with persistent trophoblast development, leading to an anembryonic gestation

Micro description
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● Villous stromal edema without central cistern formation or trophoblastic hyperplasia
● Features of karyotypic abnormalities may be present
● 52% are trisomic (smaller villi without cisterns), 20% are triploid (resemble partial moles with focal trophoblastic invaginations, cisterns, irregular surfaces and dysmorphic features) and 15% are XO and 6% are tetraploid
● Before week 8, aneuploidy is most common with embryonic growth disorganization

End of Placenta > Placental findings in specific newborn/fetal or maternal conditions > Blighted ovum

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