Placenta
Placental findings in specific newborn / fetal or maternal conditions
Blighted ovum


Topic Completed: 1 October 2011

Revised: 19 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Blighted ovum placenta

Mandolin S. Ziadie, M.D.
Page views in 2018: 2,154
Page views in 2019 to date: 1,196
Cite this page: Ziadie MS. Blighted ovum. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentablightedovum.html. Accessed July 18th, 2019.
Definition / general
  • Failure of development or early embryonic demise with persistent trophoblast development, leading to an anembryonic gestation
Microscopic (histologic) description
  • Villous stromal edema without central cistern formation or trophoblastic hyperplasia
  • Features of karyotypic abnormalities may be present
  • 52% are trisomic (smaller villi without cisterns), 20% are triploid (resemble partial moles with focal trophoblastic invaginations, cisterns, irregular surfaces and dysmorphic features) and 15% are XO and 6% are tetraploid
  • Before week 8, aneuploidy is most common with embryonic growth disorganization
Back to top