Placenta - Congenital primitive epithelial tumor of liver

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Placenta

Non-trophoblastic neoplasms

Congenital primitive epithelial tumor of liver

Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 29 November 2011, last major update November 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Case reports
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● Malignant congenital hepatic tumor diagnosed based on review of placenta (Hum Pathol 2000;31:259)

Micro description
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● Metastatic tumor consisting of polygonal cells with atypical features that invade the villous stroma and maternal vessels
● Cells have focal rhabdoid features, with abundant cytoplasm, vesicular nuclei, prominent nucleoli
● Numerous mitoses

Positive stains
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● Cytokeratin, EMA, vimentin

End of Placenta > Non-trophoblastic neoplasms > Congenital primitive epithelial tumor of liver

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