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Placenta

Placental gross/microscopic abnormalities, non-neoplastic

Geographic villi


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 10 October 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Enlarged, dysmorphic villi with scalloped outlines without associated trophoblastic hyperplasia

Etiology
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● Associated with chromosomal abnormalities including trisomies 18, 13, 21; triploidy; XO

Gross images
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Trisomy 18 infant with overlapping digits

Micro description
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● Enlarged, dysmorphic villi with scalloped outlines
● Trophoblastic invaginations may be present
● No/mild trophoblastic hyperplasia is seen

End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Geographic villi


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