Placental findings in specific newborn / fetal or maternal conditions
Hydrops fetalis

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 16 October 2017, last major update October 2011

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Hydrops fetalis [title] placenta

Cite this page: Ziadie, M. Hydrops fetalis. website. Accessed June 19th, 2018.
Definition / general
  • Massive generalized fetal edema due to a variety of processes
  • Immune related: hemolytic disease of the newborn, previously the most common cause of hydrops fetalis
  • Nonimmune related: chromosomal abnormalities, infection, congenital cardiac / other anomalies, anemia, metabolic disorders and fetal tumors
Gross description
  • Edematous placenta
Microscopic (histologic) description
  • Villous stromal edema with erythroblastosis (increased fetal nucleated red cells) and possibly intravillous hematopoiesis
  • No trophoblastic hyperplasia or cisterns (Hum Pathol 1985;16:785)
Microscopic (histologic) images

Images hosted on other servers:

Placental hydrops