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Placenta

Placental findings in specific newborn/fetal or maternal conditions

Hydrops fetalis


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 13 November 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Massive generalized fetal edema due to a variety of processes

Etiology
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● Immune related: hemolytic disease of the newborn, previously the most common cause of hydrops fetalis
● Non-immune related: chromosomal abnormalities, infection, congenital cardiac / other anomalies, anemia, metabolic disorders and fetal tumors

Gross description
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● Edematous placenta

Micro description
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● Villous stromal edema with erythroblastosis (increased fetal nucleated red cells) and possibly intravillous hematopoiesis
● No trophoblastic hyperplasia or cisterns (Hum Pathol 1985;16:785)

Micro images
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Placental hydrops

End of Placenta > Placental findings in specific newborn/fetal or maternal conditions > Hydrops fetalis


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