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Placenta

Non-trophoblastic neoplasms

Lymphoma


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 29 November 2011, last major update November 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Rare; usually of maternal origin

Case reports
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Maternal origin: 20 year old woman with anaplastic large cell lymphoma disseminated to placenta (Am J Surg Pathol 1997;21:1236)
Fetal origin: 20 week stillborn with EBV associated B cell lymphoma (Am J Surg Pathol 1999;23:595)

Micro description
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Maternal origin: tumor cells involve intervillous spaces, spare villi and fetal circulation
Fetal origin: tumor cells within villi, sparing intervillous space; molecular studies are positive for EBER1 RNA if EBV associated

End of Placenta > Non-trophoblastic neoplasms > Lymphoma


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