Placental findings in specific newborn/fetal or maternal conditions
Recurrent fetal loss
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 17 November 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
● Most common causes of intrauterine fetal death are genetic, infection, thrombotic disorders and autoimmune disease
● Other causes include environmental (smoking, alcohol) and endocrine (diabetes)
● Rate of occurrence varies based on gestational age
● Early recurrent loss is generally due to genetic abnormalities; late loss is more often associated with infection / inflammation
● First trimester: genetic (aneuploidy and other chromosomal abnormalities), thrombophilic and autoimmune
● Second and third trimester: autoimmune (antiphospholipid syndrome), uterine anatomic abnormalities (polyps, leiomyomas, septae, cervical incompetence, etc), maternal hypertension, thrombophilia and infection / inflammation
End of Placenta > Placental findings in specific newborn/fetal or maternal conditions > Recurrent fetal loss
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).