Placental findings in specific newborn / fetal or maternal conditions

Topic Completed: 1 October 2011

Revised: 19 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Scleroderma placental

Mandolin S. Ziadie, M.D.
Page views in 2018: 83
Page views in 2019 to date: 84
Cite this page: Ziadie MS. Scleroderma. website. Accessed November 21st, 2019.
Definition / general
  • Systemic sclerosis with fibrosis of multiple organs and autoimmune antibodies
  • Associated with increased risk of intrauterine fetal demise, growth restriction and premature delivery
Microscopic (histologic) description
  • Limited data shows an increased frequency of decidual vasculopathy with mural macrophages and deposition of IgM and IgG (Hum Pathol 1998;29:1524)
Back to top