Cite this page: Ziadie MS. Scleroderma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentascleroderma.html. Accessed July 21st, 2019.
Definition / general
- Systemic sclerosis with fibrosis of multiple organs and autoimmune antibodies
- Associated with increased risk of intrauterine fetal demise, growth restriction and premature delivery
Microscopic (histologic) description
- Limited data shows an increased frequency of decidual vasculopathy with mural macrophages and deposition of IgM and IgG (Hum Pathol 1998;29:1524)