Placental findings in specific newborn / fetal or maternal conditions

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 16 October 2017, last major update October 2011

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Scleroderma placental

Cite this page: Ziadie, M. Scleroderma. website. Accessed November 15th, 2018.
Definition / general
  • Systemic sclerosis with fibrosis of multiple organs and autoimmune antibodies
  • Associated with increased risk of intrauterine fetal demise, growth restriction and premature delivery
Microscopic (histologic) description
  • Limited data shows an increased frequency of decidual vasculopathy with mural macrophages and deposition of IgM and IgG (Hum Pathol 1998;29:1524)