Placenta
Placental findings in specific newborn / fetal or maternal conditions
Scleroderma

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 16 October 2017, last major update October 2011

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PubMed Search: Scleroderma placental

Cite this page: Ziadie, M. Scleroderma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentascleroderma.html. Accessed October 17th, 2017.
Definition / general
  • Systemic sclerosis with fibrosis of multiple organs and autoimmune antibodies
  • Associated with increased risk of intrauterine fetal demise, growth restriction and premature delivery
Microscopic (histologic) description
  • Limited data shows an increased frequency of decidual vasculopathy with mural macrophages and deposition of IgM and IgG (Hum Pathol 1998;29:1524)